Of course it depends on the state of play but what are the cards generally (unless in a specific situation) that you sacrifice?
For me, I'd say Freeze or Clinging Webs that disable one opponent to move for a certain amount of turns. I find killing them is more helpful.
After that I would say Engulfing Flames or Poison Gas as I find these slow.
Also, I'd say Supernova. I hardly ever use it and it cost loads.
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