The problem is that out of those 150, you will only be able to use maybe 50 or 60 cards with a specific hero. Suppose that 40 are allies of which you can only use 20 due to shadow/human restrictions, then you have 10 abilities per hero (you can use 10 out of 70), 10 abilities for shadow/human abilities (10 out of 20), plus 10 neutral and 10 armors/weapons. And out of those 60 cards, some of them are probably rubbish, some of them will make older cards unplayable, etc.
What I am trying to point out is that you will only get a small set of cards to play with in each expansion. And when you think about the physical cards it is even worst! Imagine buying a booster just to see that you got not even one card for your hero. One thing is online, where you play almost for free, another thing is paying for a booster just to find out you didn't even got one playable card. One solution would be to have boosters specific to humans and boosters specific to shadow, that would reduce the odd of getting non playable cards. Another would be to have boosters per class. Another would be to reduce the restrictions that classes impose on the cards.
I understand that balancing issues can occur, but then again it is the developers job to make sure that doesn't happen. One easy way to do that is making online pre-release tournaments every now and then on a test server with the new possible cards. Most people that like to play the game wouldn't mind trying out new hypothetical cards. If they think that is not a motivation enough, they can always through in some prizes like shadow crystals.
You said it allows for more cards to be used. Like I said before, right now you can have access to less than half a set per hero. How is that more cards? Also the
Ley Line Nexus is a great example. If I'd run a control deck, I would probably pick the Ley Line over the
Smashing Blow, because it gives you card advantage and I don't really mind over the 2 extra resources. On the other hand, if I am playing an agro deck, I would probably pick the Smashing blow as I would rather use less resources so I could cast more allies.
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